In our latest question and also answer, the pharmacist discusses even if it is or no Benadryl (diphenhydramine) can be taken v Sudafed (pseudoephedrine).

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Jerome asked

I have actually really poor congestion and also am acquisition Sudafed (pseudoephedrine) i m sorry really appears to be helping. I am having trouble sleeping and was wonder if the was safe to take it Benadryl too. I am taking Sudafed 12 hour.


Sudafed (pseudoephedrine) and Benadryl (diphenhydramine) deserve to be safe taken with each other as over there is no interaction in between the two medications. In fact, there room products easily accessible over the respond to that incorporate both ingredient to ease administration of both drugs.

Taking Benadryl and also Sudafed Together

Sudafed (pseudoephedrine) is a frequently used nasal decongestant that works by creating vasoconstriction in the nasal passages, which shrinks swollen nasal membranes and also relieves nasal congestion. Sudafed additionally acts to increase nasal airflow and also drainage that sinus secretions.

Sudafed is typically well tolerated, but one of the most common adverse reactions to that is insomnia. Sudafed have the right to have a slim stimulating effect in some, making it an overwhelming to autumn asleep easily. In fact, insomnia has actually a report incidence price of in between 4% come 10% based upon data obtained from studies.

To combat the results insomnia, Benadryl (diphenhydramine) is a potential option. In enhancement to its usage as one antihistamine, that is an effective sleep aide. Benadryl can reason pronounced sedation upon management and can assist in to decrease sleep latency (i.e. Time the takes to autumn asleep.) there is no interaction in between Benadryl and also Sudafed and also they space safe to take it together.

As pointed out above, over there are number of over the counter products that save bothingredients if you space looking to integrate the two medications. However, plenty of were stop as an outcome of thestricter lawsregarding Sudafed purchases. Many assets that originally had pseudoephedrine now contain Sudafed PE (phenylephrine).While over there still may be Benadryl (diphenhydramine)/Sudafed (pseudoephedrine) combinations available to purchase, that is an ext common to watch Benadryl and also Sudafed PE (phenylephrine) an unified with one another as these products are easily accessible to be put on save shelves and not behind the pharmacy counter.

It is vital to keep in mind that if you space taking Sudafed and also using Benadryl as a night time sleep aide, the all at once effects of Benadryl might be lessened (based top top the stimulant result of Sudafed). They have the right to nevertheless be supplied together however, as debated above.

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Sudafed is accessible in prompt release formulations, which last around four to six hours as well as extended release (e.g. 12 and 24 hour) formulations. If you are still having trouble resting while taking Sudafed and also Benadryl, the is generally prudent to avoid taking immediate release Sudafed commodities within 4 to 6 hrs of bedtime and also extended release Sudafed assets up to 12 hours before bedtime.